- Class: Benzimidazole proton pump inhibitor
- Action: It is a gastric acid (proton) pump inhibitor. In an acidic environment, it is activated to a sulphenamide derivative that binds irreversibly at the secretory surface of parietal cells to the enzyme, H+/K+ ATPase. There it inhibits the transport of hydrogen ions into the stomach. It inhibits acid secretion during both basal and stimulated conditions. It also inhibits the hepatic cytochrome P-450 mixed function oxidase system.
- Indication: Gastroduodenal ulcers, Gastritis
- Dosage: Oral, IV
Dog: 0.5 - 1 mg/kg OD
Cats: 0.7 mg/kg OD
