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Friday, 20 May 2016

Metoclopramide


  • Class: Anti emetic
  • Action: It stimulates motility of the upper GI without stimulating gastric, pancreatic or biliary secretions. In the CNS, it apparently antagonizes dopamine at the receptor sites. This action can explain its sedative, central anti-emetic (blocks dopamine in the chemo-receptor trigger zone), extrapyrimidal, and prolactin secretion stimulation effects.
  • Indications: Vomiting due to gastritis, impaction, esophageal reflex
  • Dosage:               SC, IM, IV, Oral
                Dog, Cat: 0.2 - 0.4 mg/kg