- Class: Anti muscarinic
- Action: It competitively inhibits acetylcholine or other cholinergic stimulants at postganglionic parasympathetic neuroeffector sites. High doses may block nicotinic receptors at the autonomic ganglia and at the neuromuscular junction.
- Pharmacologic effects: Dose related. At low doses salivation, bronchial secretions, and sweating (not horses) are inhibited. At moderate systemic doses, atropine dilates and inhibits accommodation of the pupil, and increases heart rate. High doses will decrease GI and urinary tract motility. Very high doses will inhibit gastric secretion.
- Indications: Preanesthetic to prevent or reduce secretions of the respiratory tract Treat sinus bradycardia, sinoatrial arrest, incomplete AV block, Hypersialism and bronchoconstrictive disease, As an antidote for overdoses of cholinergic agents (e.g., physostigmine, etc.) As an antidote for organophosphate or muscarinic mushroom intoxication.
- Doasge: IM, IV, SC